Clinical Evaluation of Polycystic Ovary Syndrome

Eligibility Details: Inclusion Criteria: - Aged >18 years - At least 2y post-menarche - BMI >18.5kg/m2 - Good visibility of the ovaries on ultrasound - Pelvic exam with normal results within the last 2 years Either: - Regular menstrual cycles (21-35 days); - Irregular menstrual cycles (>36 days); or - Previous diagnosis of PCOS from a primary care provider Exclusion Criteria: - Use of medication(s) known or suspected to interfere with reproductive function, metabolism, and/or appetite (e.g., oral contraceptives) within the past 3 months - Use of fertility medications in the past 2 months (e.g., Clomid) - Current use of a non-copper intrauterine device for contraception (e.g., Mirena) - Diagnosis of premature ovarian failure, endometriosis, or another disease/disorder (other than PCOS) known or suspected to interfere with reproductive function - History of ovarian surgery - Missing uterus or an ovary - Pregnant or breastfeeding - Diagnosis of a bleeding disorder - Regular use of blood thinners/anticoagulants - Skin allergy/condition that might be aggravated by alcohol application - Currently being treated for a vaginal infection, cervical infection, sexually transmitted infection, or disease either with antibiotics, antifungals, or anti-viral medication - Abnormal vaginal discharge, pelvic pain, and/or blisters/lesions/warts/skin growths in the genital/anal area, which have not been examined by a medical professional. - Vaginal abnormality (e.g., vaginal atresia/hypoplasia, vaginal septation, Mullerian agenesis, vulvar/vaginal malignancy). - Not otherwise healthy