Clinical Trial

Gene Expression and Biomarker Profiling of Keloid Skin

Study Description

Gene Expression and Biomarker Profiling of Keloid Skin

This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: 1. Differences in the genetic profiles of lesional and non-lesional skin contribute a given population's propensity to develop keloids 2. Differences in biomolecules expressed in subjects with and without keloids can help predict keloid occurrence and severity 3. Biomarker analysis will provide useful insights for future targeted therapies for keloid scars

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Procedure - Biopsy and/or triamcinolone injection

Subjects will have their blood drawn during the first study visit. Subsequently, a punch biopsy and/or triamcinolone injection will be given based on group timeline.

Procedure - Excisional Biopsy

Complete excision of an earlobe keloid will be taken.

Additional Information

Official Study Title

Gene Expression and Biomarker Profiling of Keloid Skin

Clinical Trial ID

NCT03228693

ParticipAid ID

lejm5d