Clinical Trial

Randomized on-X Anticoagulation Trial

Study Description

Randomized On-X Anticoagulation Trial

Various patient groups with the On-X Valve can be maintained safely on lower doses of blood thinner(CoumadinAR) or on antiplatelet drugs (aspirin/PlavixAR) only rather than the standard dose of Coumadin and aspirin presently recommended by ACC/AHA or ACCP professional societies.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Recruiting patients only Recruiting patients only

Device - On-X valve using reduced anticoagulation

Valve replacement with antiplatelet agents or lowered warfarin

Device - On-X Valve with Standard warfarin Therapy

Valve replacement with standard dosage warfarin

Additional Information

Official Study Title

Prospective Randomized On-X Anticoagulation Clinical Trial (PROACT)

Clinical Trial ID

NCT00291525

ParticipAid ID

mepY2a