“Role of Polyunsaturated Fatty Acids (PUFA)-Gene Interactions in Heath Disparities”
A randomized, clinical trial to provide the first comprehensive investigation of the role of fatty acid desaturate (FADS) genetic determinants on PUFA biosynthesis and metabolism as well as levels of inflammatory markers in a controlled dietary environment using two (low and high linoleic acid) parallel diets.
Dietary Supplement - High Linoleic Acid (LA) Diet
Volunteers will be randomly assigned to consumption of a high [10% energy] LA-containing diet for 12 weeks.
Dietary Supplement - Low Linoleic Acid (LA) Diet
Volunteers will be randomly assigned to consumption of a low [2.5% energy] LA-containing diet for 12 weeks.
Role of PUFA-Gene Interactions in Health Disparities