Manipulating Tobacco Constituents in Male Menthol Smokers

Eligibility Details: Inclusion Criteria: 1. smoking at least 5 menthol cigarettes daily for the last year; 2. able to speak, read and understand English; 3. male age 18 -45 years of age; 4. stable residence; 5. not intending to quit smoking within the next 6 weeks. Exclusion Criteria: 1. unstable psychiatric disorder (Psychiatric symptoms reported that cause current significant impairment in functioning or judgment such that the person's ability to come consistently for study appointments or render a decision regarding informed consent is in question.); 2. substance use which exceeds any of the following: marijuana use 3x/week, consuming 21 drinks/week or illicit drug use 1x/week; 3. history of cardiovascular disease; 4. current blood clot in arms or legs; 5. blood pressure >160/100; 6. unstable medical problems which may include but are not limited to immune system disorders, severe respiratory diseases, kidney or liver diseases, thyroid problems, substance abuse or dependence that would limit patients ability to follow experimental protocol 7. Serious quit attempts in the last 3 months; 8. regular use (e.g., greater than weekly) of tobacco products other than cigarettes; 9. currently using nicotine replacement or other tobacco cessation products