Clinical Trial

Riboflavin on Moderate to Severe Plaque Type Psoriasis

Study Description

The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis

The purpose of this study is to determine the anti-inflammatory effect of high-dose riboflavin supplementation on chronic plaque psoriasis. Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directed at controlling patients' symptoms. Amongst patients with skin disease, there is significant interest in using complementary alternative medicine and vitamins to treat their disease. Previous human case reports suggest that riboflavin, commonly known as Vitamin B2, is clinically effective for the treatment of psoriasis; however, they were not conclusive. More recent human trials have shown that 400 mg of daily oral riboflavin is a safe and well-tolerated medication to administer to humans. For the purpose of this study, the riboflavin is used as an investigational drug.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Riboflavin

Riboflavin (Vitamin B2) 400 mg capsule taken daily for 12 weeks.

Placebo

Matching placebo capsule taken daily for 12 weeks.

Additional Information

Official Study Title

The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis

Clinical Trial ID

NCT02622386

ParticipAid ID

vbm8na