Clinical Trial

PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors

Study Description

PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors

The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis. The investigator also wants to define the long-term physical and cognitive outcomes of this disease. The investigator will be looking at many clinical variables to try to define CCI.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Blood collection

Blood will be collected from patient at baseline, day 1, day 4, day 7 and weekly until week 6 as long as the patient is still hospitalized. Blood will also be collected at the one year appointment.

Urine collection

Urine will be collected from patient at baseline, day 1, day 4, day 7 and weekly until week 6 as long as the patient is still hospitalized. Urine will also be collected at the one year appointment.

Bioimpedance Analysis

The bioimpedance analysis will be performed at baseline, day 14 or discharge from hospitalization, month 3, month 6, and month 12.

Cognitive Function Tests

Cognitive function tests will be administered at 3, 6 and 12 months.

Quality-of-life Questionnaires

Quality-of-life questionnaires will be administered at baseline, 3, 6 and 12 months.

Physical Function Tests

Physical function tests will be administered at baseline, day 14 or discharge from hospital 3, 6 and 12 months.

Blood Collection

The healthy volunteer participants will donate a blood sample. These controls will allow the investigators to determine if the values obtained are accurate, reliable, and repeatable.

Additional Information

Official Study Title

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care Subtitle: Cardiac Dysfunction in Older Sepsis Survivors

Clinical Trial ID

NCT02276417

ParticipAid ID

vbmEAb