Clinical Trial

APOA2 Gene, Diet, Inflammation and Gut Health

Study Description

APOA2 Gene, Diet, Inflammation and Gut Health

Nutrients and chemicals in food are able to regulate expression of genetic elements. Gene-nutrient interaction in response to unhealthy diets can increase an individual's risk, shifting the individual from health toward the development of chronic disease. The apolipoprotein A2 (APOA2) gene may either put individuals at risk for or protect from obesity in the presence of certain fats in food. The main purpose of this four-week study is to examine diet induced gene-nutrient interaction, with a focus on gut health, gut microbiota and inflammation in individuals who have either the CC or the TT form within a specific variant of the APOA2 Gene. The (2) one-week study diets, one plant based and the other animal based are separated by a (1) week return to your regular habitual without probiotic or prebiotic food products.

Location

Locations Selected Location

Methods

No pharmaceutical medication involved No pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Animal Diet

during one week participants will receive food products enriched in animal products and with high content of fat and protein

Plant Diet

during one week participants will receive plant products enriched in fiber and complex carbohydrates

Additional Information

Official Study Title

APOA2 Gene, Diet, Inflammation and Gut Health

Clinical Trial ID

NCT03322449

ParticipAid ID

xbo1Ne