Circulating Innate Lymphoid Cells in Allergic Disorders

Eligibility Details: Inclusion Criteria: 1. Adult subjects between age 19-50 years. 2. Non-smokers, defined as < 100 cigarettes in lifetime. Exclusion Criteria: 1. Female donors will be excluded if they are menopausal or have undergone total abdominal hysterectomy and/or bilateral salpingoophorectomy 2. For female donors, blood draw cannot occur during menstrual period time. Subjects will be excluded if they have menstrual period at timing of blood draw. 3. Current and past smokers. 4. Subjects with asthma and any other lung disease including chronic obstructive pulmonary disease, interstitial lung disease, pulmonary hypertension, sarcoidosis, cystic fibrosis. 5. Pregnant or lactating subjects 6. Subjects with hypercalcemia (> 10.3 mg/dL), renal insufficiency (glomerular filtration rate [GFR] < 50 mL/min/1.73m2), or malignancy. 7. Subjects with any symptoms of respiratory infection in the past 4 weeks. 8. Subjects unable to hold leukotriene modifiers or antihistamines for at least 24 hours prior to blood draw. 9. Subjects on any immunomodulators, including omalizumab, or systemic corticosteroid in the past 4 weeks.