Clinical Trial

Oral Cholera Vaccine

Study Description

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

The primary objective of this study is to evaluate the antibody response to the cholera vaccine, VaxchoraAR, in healthy subjects. Investigators also seek to evaluate additional markers of the adaptive immune response including plasmablasts, activated B cells, memory B cells, and T cell responses in healthy subjects receiving cholera vaccine, produce monoclonal antibodies against cholera, and evaluate the safety and reactogenicity in healthy subjects receiving cholera vaccine.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - Vaxchora

Vaxchora is a live attenuated cholera vaccine that provides immunity against V. cholerae serogroup O1. Participants will receive one single oral dose of 100 mL.

Additional Information

Official Study Title

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

Clinical Trial ID

NCT03251495

ParticipAid ID

yb8Lob