“Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation”
The purpose of the study is to develop advanced ultrasound (U/S) and Magnetic Resonance Imaging, known as MRI to study uteroplacental health. The goal of this study is to evaluate the blood and oxygen flow to the placenta using advanced U/S and MRI testing.
Procedure - Ultrasound Scan
The research exam is expected to take 30 minutes for blood flow assessments
Procedure - MRI Scan
MR imaging will take approximately 30 minutes.
Drug - Ferumoxytol
A subset of subjects will complete MRI imaging with ferumoxytol as a contrast agent at the 24-28 week visit. A nurse will administer ferumoxytol in a hospital triage with pulse and blood pressure monitoring and fetal heart monitoring. The pharmacy will prepare the infusion and deliver to triage. Subjects will arrive at the obstetric triage unit for ferumoxytol injection three days prior to their scheduled ferumoxytol MRI study. In the triage, the nurse will obtain baseline vital signs and fetal ...read more on ClinicalTrials.org
Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation