Clinical Trial

MRI for Uteroplacental Flow Oxygenation & Inflammation

Study Description

Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation

The purpose of the study is to develop advanced ultrasound (U/S) and Magnetic Resonance Imaging, known as MRI to study uteroplacental health. The goal of this study is to evaluate the blood and oxygen flow to the placenta using advanced U/S and MRI testing.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Procedure - Ultrasound Scan

The research exam is expected to take 30 minutes for blood flow assessments

Procedure - MRI Scan

MR imaging will take approximately 30 minutes.

Drug - Ferumoxytol

A subset of subjects will complete MRI imaging with ferumoxytol as a contrast agent at the 24-28 week visit. A nurse will administer ferumoxytol in a hospital triage with pulse and blood pressure monitoring and fetal heart monitoring. The pharmacy will prepare the infusion and deliver to triage. Subjects will arrive at the obstetric triage unit for ferumoxytol injection three days prior to their scheduled ferumoxytol MRI study. In the triage, the nurse will obtain baseline vital signs and fetal ...read more on ClinicalTrials.org

Additional Information

Official Study Title

Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation

Clinical Trial ID

NCT02791568

ParticipAid ID

yb8zje