Exercise and Brain Health

Eligibility Details: Inclusion Criteria: - Adequate language and neurocognitive function to participate in testing and training and to give adequate informed consent - Able to rise from a chair unaided - Completion of all regular post-stroke physical therapy (if applicable) - Able to walk 30 feet without human assistance Exclusion Criteria: - Clinical history of - unstable angina - recent (< 3 months) myocardial infarction or congestive heart failure (NYHA category II) - hemodynamically significant valvular dysfunction - peripheral arterial obstructive disorder with claudication - major orthopedic, chronic pain, or non-stroke neuromuscular disorders restricting exercise - pulmonary or renal failure - poorly controlled hypertension (>190/110), measured on at least two separate occasions - recent hospitalization for severe disease or surgery - severe or global receptive aphasia which confounds reliable testing and training - Other medical condition precluding patient participation in this study as per medical judgment of study team - Untreated major depression - Pregnancy - Alcohol consumption > 3 oz. liquor, or 3 x 4 oz glasses of wine, or 3 x 12 oz. beers per day, by self-report - Dementia and other major cognitive deficits (based upon clinical evaluation)