Clinical Trial

PET/MRI in the Diagnosis of Chronic Pain

Study Description

PET/MRI in the Diagnosis of Chronic Pain

Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using [18F]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.

Location

Locations Selected Location

Methods

Pharmaceutical medication involved Pharmaceutical medication involved
Patients and healthy individuals accepted Patients and healthy individuals accepted

Drug - [18F]FTC-146

Adult participants will be injected with 5-10 mCi of [18F]FTC-146 and undergo a PET/MRI scan.

Additional Information

Official Study Title

Use of [18F]FTC-146 PET/MRI in the Diagnosis of Chronic Pain

Clinical Trial ID

NCT03556137

ParticipAid ID

zbqwpe